INTERLEUKIN-18 (IL-18) ACTIVATES NATURAL KILLER (NK) CELLA AND INDUCES TUMOR APOPTOSIS
نویسندگان
چکیده
منابع مشابه
Interleukin (IL)-18 Binding Protein Deficiency Disrupts Natural Killer Cell Maturation and Diminishes Circulating IL-18
The cytokine interleukin (IL)-18 is a crucial amplifier of natural killer (NK) cell function. IL-18 signaling is regulated by the inhibitory effects of IL-18 binding protein (IL-18BP). Using mice deficient in IL-18BP (IL-18BPKO), we investigated the impact of mismanaged IL-18 signaling on NK cells. We found an overall reduced abundance of splenic NK cells in the absence of IL-18BP. Closer exami...
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ژورنال
عنوان ژورنال: Japanese jornal of Head and Neck Cancer
سال: 2003
ISSN: 1883-9878,0911-4335
DOI: 10.5981/jjhnc1974.29.217